Unlike with previous versions of Windows Server--in which you could disable Internet Explorer Enhanced Security Configuration by removing the component in Add/Remove Programs, Windows Components--the Windows Server 2008 implementation of Internet Explorer Enhanced Security Configuration is configured through Server Manager. Select the root of the Service Manager navigation pane, and under the Server Summary click Configure IE ESC, which is part of the Security Information section. A dialog box appears, ......
We recently had to open a ticket with MS regarding the creation of workflows when using Infopath. Basically what would happen is that the connection to the SQL box was so slow that the XML was not getting created on the workflow. We're running IE8 with Win 7, X64.
THE SOLUTION: Go into IE -> choose tools -> connections -> LAN settings and uncheck the auto detect option.
Hope that helps someone.