Sysprep creates a snapshot of a virtual machine with BizTalk Server 2010 installed for quick deployment on other virtual machines
Before using Sysprep, you should have some knowledge of using virtual machines with Hyper-V. You should also have a virtual machine with a clean, typical installation of BizTalk Server and all of its prerequisites.
Sysprep will run on Windows Server 2008 and Windows Vista with SP1.
Sysprep creates a VHD of a BizTalk Server 2010 installation (including the operating system and all prerequisites) for quick deployment on other virtual machines. An image created using Sysprep will choose a new computer name in order to join the domain the first time it starts. To get BizTalk Server running properly, it is necessary to update various instances of the computer name that are stored in the registry and databases.
Please refer the Microsoft Links for Details :http://technet.microsoft.com/en-us/library/ee358636.aspx