This one had me stumped for a while, turns out it was extremely simple and I just wanted to share. Here's the setup: <iframe id="Iframe1" frameborder="1" marginwidth="0" marginheight="0" width="745" scrolling="no" height="445" style="position:absolute;to... src="somepage.aspx"><... In the somepage.aspx I had a datalist with a SELECT command argument which updated an object on the server, then on the OnClientClick ......