Here is the list of Fast and Light Functions and Costly Functions. So when you write your next piece of codes be more careful to choose the right methods.
Fast and Light Functions
typeof
Object.GetType
typeof == Object.GetType
Type equivalence APIs (including typehandle operator overloads)
get_Module
get_MemberType
Some of the IsXX predicate APIs
New token/handle resolution APIs in the .NET Framework 2.0
Costly Functions
GetXX APIs (MethodInfo, PropertyInfo, FieldInfo, and so on)
GetCustomAttributes
Type.InvokeMember
Invoke APIs (MethodInfo.Invoke, FieldInfo.GetValue, and so on)
get_Name (Name property)
Activator.CreateInstance