Problem
This is not an uncommon error in the picture below, you import the bindings and get an error related to your hosts and the port bindings. I had a look at the host settings and everything seemed fine so i was stumpted for a while. I was using custom hosts for this rather than the default BizTalk ones.

Solution
After a bit of digging i realised the problem was i hadnt setup the send and recieve handlers for this host and the appropriate adapter. So in this case i added my host as a send handler on the File adapter then re-imported the bindings and all was fine.