I ran into the error, below, because the host instance didn't have permissions to read the C:\Program Files\Microsoft BizTalk ESB Toolkit 2.0\esb.config file. Also, don't forget to restart your host instance (or run iisreset) after you update your permissions. Event Type: Error Event Source: BizTalk ESB Toolkit 2.0 Event Category: None Event ID: 6060 Date: 2/9/2010 Time: 2:03:58 PM User: N/A Computer: XXXXXXXXXXXXX Description: Error 194008: An error occurred reading the, esb, Section in the config...