Many interesting projects are showing up on www.CodePlex.com such as the Best Practices Analyzer. This tool is an engine for analyzing applications for Best Practices Compliance. The tool is Shared Source and is architected using a "Plug-In" design. This means the tool is easily extendible via new Plug-Ins and rules.
Perhaps Garbage Collection is spoiling us as developers. The Garbage Collector is kind of like our own maid following us around picking up every mess we create. Anway, .NET does a great job managing many resources for us including things like memory and conncetion pooling. However, this doesn't mean we are completely off the hook.
The ClickOnce Resource Kit download includes a 70 page how-to with best practices for implementing ClickOnce. The resource kit also provides utilities to help reduce the amount of manual procedures needed to create a Manifest.